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Which one of the following will travel fastest through the gel if the amount of DNA present is same in all?

Filza

20 Jun, 2022

A. Circular

B. Supercoiled

C. Nicked

D. Supercoiled and circular will move at the same speed and faster than nicked

Explanation: The supercoiled form of DNA will travel the fastest. It is so because; the movement through the gel is based on the size. The smaller the molecule is the less retarding force it experiences when it moves. Hence, supercoiled which is having the smallest size will move the fastest.

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